Roger Bernadina’s RBI double in the seventh increased Washington’s lead to 5-2.
Tampa Bay scored in the second when Hideki Matsui walked and Jose Lobaton, Drew Sutton and Desmond Jennings singled.
The Nationals scored twice in the third off Matt Moore. Espinosa and Bryce Harper led off with walks, then pulled off a double steal. Michael Morse had a sacrifice fly and Desmond had an RBI single.
The Rays made it 2-all in the sixth on Ben Zobrist’s leadoff double and a one-out single by Sean Rodriguez.
Moore worked five innings. He allowed two runs and three hits, walking four and striking out six.